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11th ICID - Cancun, Mexico - March 4-7, 2004

Plenary Lectures
Of Flies and Men: The Role of Toll-like Receptors in Innate Immunity
Shizuo AKIRA, Japan

Shizuo Akira is now a professor at the Research Institute for Microbial Diseases at Osaka University, Japan. He received his M.D. in 1977 and Ph.D. in 1984 from Osaka University. After postdoctoral work in the Department of Immunology, University of California at Berkeley, he studied IL-6 gene regulation and signaling at the Institute for Molecular and Cellular Biology, Osaka University, and cloned transcription factors NF-IL6 (also known as C/EBP beta) and STAT3. His current research interests are molecular mechanisms of host defense and innate immunity, which he studies primarily by generating knockout mice.
Community-Based Therapy for AIDS and Drug-Resistant Tuberculosis in Resource-Poor Settings

Paul FARMER, USA

Paul Farmer, M.D., Ph.D., is the Maude and Lillian Presley Professor of Medical Anthropology at Harvard Medical School and Medical Director of the Clinique Bon Sauveur, a charity hospital in rural Haiti. An infectious disease physician as well as anthropologist, Dr. Farmer has worked in communicable-disease control in the Americas for over a decade. Along with his colleagues in the Program in Infectious Disease and Social Change in the Department of Social Medicine at Harvard Medical School, Dr. Farmer has pioneered novel, community-based treatment strategies for tuberculosis—and also sexually transmitted infections (including HIV) and drug-resistant typhoid—in resource-poor settings. Dr. Farmer is Vice Chief of Brigham and Women’s Hospital’s Division of Social Medicine and Health Inequalities.

Genetic Susceptibility to Infectious Diseases: Genomic Approaches

Adrian HILL, UK

Professor Adrian V. S. Hill is a Wellcome Trust Principal Research Fellow at the Institute of Molecular Medicine and Wellcome Trust Centre for Human Genetics at the University of Oxford. He qualified for Oxford Clinical School in 1982 and undertook a DPhil in human population genetics at the MRC Molecular Haematology Unit. Following clinical training, he returned to Oxford in 1988 to the Institute of Molecular Medicine. With collaborators in Africa and Asia he has made contributions to the genetics of susceptibility to several infectious diseases, especially malaria and tuberculosis, and to vaccine design and development. His group has recently been undertaking clinical trials of new T cell-inducing malaria vaccines. He is a Fellow of the Royal College of Physicians and of the UK Academy of Medical Sciences.

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Reverse Vaccinology: Using Genome Information to Develop New Vaccines

Rino RAPPUOLI, Italy

Rino Rappuoli is responsible for Chiron Vaccines Research. After earning his PhD in Biological Sciences from the University of Siena, he studied at Washington University of St. Louis, Rockefeller University and Harvard Medical School. He is recipient of the Paul Ehrlich Prize and other prestigious awards and has authored or co-authored 257 original papers, 42 reviews, 31 chapters, and 97 congress proceedings and eight edited volumes. His field of expertise is vaccines, bacterial pathogenesis, and infectious diseases. Dr. Rappuoli is member of several international societies and committees, including the European Molecular Biology Organization; R&D working group of the European Vaccines Manufacturers; Scientific Committee of the Paul Ehrlich Foundation; and External Advisory Group for "Control of Infectious Diseases" of the European Union. He is co-chairman of the R/D Task Force of the Global Alliance for Vaccines and Immunization (GAVI).

Cholera in Latin America: The Paradoxical Benefits of the Last Pandemic
Jaime SEPULVEDA , Mexico

Jaime Sepúlveda is in his second term as the Director General of the National Institute of Public Health in Mexico. His priorities have included two national surveys, the National Health Survey 2000, and the National Survey on Nutrition II, as well as the seroepidemiology of infectious diseases, effective strategies for the control of chronic diseases, and epidemiological surveillance. Involved in Mexican health care at the national level for nearly 20 years, he has also been active in health data collection, analysis, and educational campaigns. Dr. Sepúlveda is a founder of the National AIDS Council (CONASIDA), and the National Vaccination Council (CONAVA), which brought about the eradication of polio in México. He has played important roles internationally in the vaccine and prevention initiatives of such organizations as UNAIDS, WHO, and the CDC.
A Hidden Epidemic: The HTLV-I Story in Latin America
Eduardo GOTUZZO , Peru

Eduardo Gotuzzo is the Principal Professor of Medicine, Infectious Diseases, and Tropical Medicine at Universidad Peruana Cayetano Heredia in Lima, Peru, where he also directs the the first ID residency program in that country. He also serves as director of both the Alexander von Humboldt Institute of Tropical Medicine and the Gorgas Course in Clinical Tropical Medicine.
A past president of ISID, Dr. Gotuzzo is also former president of the Peruvian Society for Internal Medicine and the PanAmerican Infectious Diseases Association.
With more than 250 publications to his credit, Dr. Gotuzzo's longtime research interests -- enteric diseases, TB, HIV, and emerging diseases -- have broadened to include analyzing recurrent clinical patterns among one of the largest cohorts of HTLV-I patients.
Dr. Gotuzzo is active on the editorial boards of such journals as Infectious Diseases for Clinical Practice and Journal of Travel Medicine. He is an honorary member of the ASTMH, an associate member of the National Academy of Medicine, and a member of the Institute of Medicine's Forum on Emerging Infections.

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